KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEK
All Species:
22.73
Human Site:
S43
Identified Species:
50
UniProt:
P08567
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08567
NP_002655.2
350
40097
S43
Y
K
K
K
S
D
N
S
P
K
G
M
I
P
L
Chimpanzee
Pan troglodytes
XP_515524
350
40124
S43
Y
K
K
K
S
D
N
S
P
K
G
M
I
P
L
Rhesus Macaque
Macaca mulatta
XP_001094492
350
40060
S43
Y
K
K
K
S
D
N
S
P
K
G
M
I
P
L
Dog
Lupus familis
XP_537486
375
42096
P68
D
G
G
R
K
V
T
P
P
K
G
R
I
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHK5
350
39882
S43
Y
K
K
K
S
D
N
S
P
K
G
M
I
P
L
Rat
Rattus norvegicus
Q4KM33
350
39977
N43
Y
K
K
K
S
D
N
N
P
K
G
M
I
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512767
334
37917
E45
S
L
Q
S
P
C
Q
E
F
G
K
R
M
F
V
Chicken
Gallus gallus
NP_990194
353
40280
S45
Y
K
R
K
S
D
N
S
P
K
G
M
I
P
L
Frog
Xenopus laevis
NP_001080021
289
33430
S44
Y
K
K
K
T
D
N
S
P
K
G
M
I
P
L
Zebra Danio
Brachydanio rerio
NP_957135
352
40176
N43
F
K
K
K
T
D
R
N
A
K
G
M
I
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781827
375
42698
L45
Y
K
Q
T
T
D
S
L
P
A
G
V
I
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
36
N.A.
92
92
N.A.
80.5
81.5
63.1
67.3
N.A.
N.A.
N.A.
N.A.
34.4
Protein Similarity:
100
100
100
55.7
N.A.
96.8
97.1
N.A.
89.4
90.6
73.7
83.8
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Identity:
100
100
100
33.3
N.A.
100
93.3
N.A.
0
93.3
93.3
66.6
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
20
100
100
86.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
82
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% F
% Gly:
0
10
10
0
0
0
0
0
0
10
91
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
91
0
0
% I
% Lys:
0
82
64
73
10
0
0
0
0
82
10
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
10
0
0
0
0
0
10
91
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
73
10
0
0
% M
% Asn:
0
0
0
0
0
0
64
19
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
10
82
0
0
0
0
73
0
% P
% Gln:
0
0
19
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
0
10
0
0
0
0
19
0
0
0
% R
% Ser:
10
0
0
10
55
0
10
55
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
28
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _